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FLIP anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-FLIP a été validé pour WB, ELISA, IHC, IF et FM. Il convient pour détecter FLIP dans des échantillons de Humain.
Rockland
N° du produit ABIN7540512
N° du produit (Fournisseur): 200-401-983

Aperçu rapide pour FLIP anticorps (C-Term) (ABIN7540512)

Antigène

Voir toutes FLIP (CFLAR) Anticorps
FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Reactivité

  • 101
  • 67
  • 57
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 91
  • 15
  • 2
Lapin

Clonalité

  • 93
  • 15
Polyclonal

Conjugué

  • 54
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp FLIP est non-conjugé

Application

  • 97
  • 39
  • 26
  • 26
  • 19
  • 17
  • 16
  • 13
  • 13
  • 10
  • 9
  • 5
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)
  • Épitope

    • 16
    • 15
    • 15
    • 10
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    N° du produit (Fournisseur)

    200-401-983

    Fournisseur

    Rockland

    Fonction

    FLIP Alpha Antibody

    Purification

    Anti-FLIP Antibody is affinity chromatography purified via peptide column. The product was purified from monospecific antiserum by DEAE ion exchange chromatography.

    Stérilité

    Sterile filtered

    Immunogène

    FLIP Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of the human FLIPalpha/FLIPL protein.

    Isotype

    IgG
  • Indications d'application

    ELISA_Dilution: User Optimized

    IF_Microscopy_Dilution: 10 μg/mL

    Western_Blot_Dilution: 0.5-1 μg/mL

    Other: ICC: 10 μg/mL

    Commentaires

    FLIP Antibody has been tested for use in ELISA, western blotting, Immunofluorescence, and Immunohistochemistry.  HeLa whole cell lysate can be used as a positive control in western blotting, and a band at approximately 55 kDa is expected. Specific conditions for reactivity should be optimized by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.02 % (w/v) Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Date de péremption

    12 months
  • Antigène

    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

    Autre désignation

    CFLAR

    Sujet

    C FLIP antibody, c FLIPL antibody, c FLIPR antibody, c FLIPS antibody, CASH antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator precursor antibody, CASP8 antibody, CASP8AP1 antibody, FLIP-L, CLARP1, MRIT alpha-1, CASH alpha, I-FLICE 1, FLAME-1 gamma,Apoptosis is related to many diseases and is induced by a family of cell death receptors and their ligands.  Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE/CED-3 protease family.  Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family.  FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively.  The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP.  FLIP contains two death effector domains (DEDs) and a caspase-like domain.  FLIP interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors.  Four splice variants of FLIPs have been identified and termed FLIP α, β, γ, and δ, respectively. Anti-FLIP antibody is ideal for investigators involved in Apoptosis, Cytokines and Growth factor research.

    ID gène

    8837, 187608571

    UniProt

    O15519

    Pathways

    Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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